In addition to glycochondroitin and mecobalamine, what other drugs can be used for the treatment of cervical disc herniation?

Non-steroidal anti-inflammatory drugs
How it works: A herniated cervical disc can cause inflammation such as neck pain, stiffness, and radiating pain in the upper extremities. Non-steroidal anti-inflammatory drugs (NSAIDs) can inhibit the activity of cyclooxygenase (COX) and reduce prostaglandin synthesis, thereby reducing inflammation and pain.
Example:
Ibuprofen: is a commonly used non-steroidal anti-inflammatory drug that reliefs pain and inflammation by inhibiting the production of inflammatory mediators in the body. The general oral dose is 200-400 mg every 4-6 hours (adjusted for pain level and individual differences). Its advantage is that the effect is relatively fast, the price is relatively cheap, can effectively reduce the pain and muscle tension caused by cervical disc herniation.
Celecoxib: It is a selective COX-2 inhibitor with relatively little irritation to the gastrointestinal tract. The usual dose is 200mg 1-2 times daily. Celecoxib is a good option for patients who cannot tolerate the gastrointestinal side effects of conventional NSaids.
Muscle relaxant
How it works: When a cervical disc herniates, the muscles in the neck are often strained and spasmosed in an attempt to protect the neck from further damage. Muscle relaxants can act on the central nervous system or peripheral nervous system to relax muscles, thereby relieving muscle tension and pain.
Example:
Clozoxazone: It mainly acts on the spinal cord and subcortical areas of the brain, producing muscle relaxation. The general oral dose is 250-500 mg each time, 3-4 times a day. It can relieve neck muscle spasms caused by cervical disc herniation and reduce pain.
Eperisone: reduces muscle tension by inhibiting spinal reflex. Adults usually take 50mg once, 3 times a day after meals. It can not only relax muscles, but also improve local blood circulation, which is helpful to relieve the symptoms of cervical disc herniation.
Dehydrating agent
How it works: When a herniated cervical disc causes compression of the nerve root or spinal cord, edema may occur in the surrounding tissue. Dehydrating agents can reduce this edema and reduce disc pressure on nerve tissue, thereby relieving symptoms.
Example:
Mannitol: It is a commonly used dehydrating agent that reduces tissue edema by increasing plasma osmotic pressure and transferring interstitial fluid to plasma. Generally, intravenous drip is used, and the common dose is 125-250ml each time, rapid drip, and can be used every 6-8 hours according to the condition. Use in acute episodes of cervical disc herniation with obvious symptoms of nerve compression and edema.
glucocorticoid
Rationale: Glucocorticoids have a powerful anti-inflammatory effect, can reduce the inflammation and edema caused by cervical disc herniation, and suppress the immune response. It stabilizes lysosomal membranes, reduces the release of inflammatory mediators, and relieves pain and nerve compression symptoms.
Example:
Prednisone: It is generally administered orally, with an initial dose of 10-60 mg per day (adjusted according to the severity of the condition), which is gradually reduced after symptoms are relieved. However, glucocorticoids have more side effects, such as osteoporosis, elevated blood sugar, digestive tract ulcers, etc., so they are generally not used for a long time, mainly for acute episodes of cervical disc herniation and serious symptoms.
Neurotrophic drugs (except mecobalamine)
Principle: These drugs can promote nerve repair and regeneration, improve nerve function.
Example:
Ganglioside: It promotes nerve remodeling, including nerve cell survival, axon growth, and synaptic formation. Generally, intramuscular injection is used, and the dosage depends on the product instructions and the condition. It has a certain auxiliary effect on improving nerve injury caused by cervical disc herniation.