Can ibuprofen and compound paracetamol bromide capsules be taken together?

Ibuprofen and compound paracetamol bromin capsules are not recommended to be taken together, as explained below:
Pharmacological cause
Some of the components in ibuprofen and compound amphenol bromin capsules have similar mechanisms of action and adverse effects, and taking them together increases the associated risk.
Mechanism of action: Ibuprofen and acetaminophen are non-steroidal anti-inflammatory drugs (NSAIDs), which reduce prostaglandin synthesis by inhibiting the activity of cycoperoxidase (COX), thereby reducing inflammation and pain perception. When taken together, the two drugs in this pathway of action will create a superposition, although theoretically may enhance the analgesic and antipyretic effect, but also greatly increase the chance of adverse reactions.
Adverse reactions: Both drugs may cause irritation to the gastrointestinal mucosa, and taking them together can significantly increase the risk of gastrointestinal discomfort, such as nausea, vomiting, abdominal pain, ulcers, and even gastrointestinal bleeding. At the same time, they also have a certain potential burden on the kidney, the combination may affect the blood perfusion and normal function of the kidney, long-term or improper use may lead to kidney damage.
Analysis of components of compound paraminophen bromin capsules
Compound paracetamol bromin capsule contains acetaminophen, bromohexine hydrochloride, chlorpheniramine maleate, caffeine and other ingredients. Among them, acetaminophen and ibuprofen have similar effects, both of which have antipyretic and analgesic effects. If the two are taken together, it is equivalent to increasing the dose of such drugs, beyond the normal safe dosage range, which will bring unnecessary risks to the body.
When you need to relieve pain or reduce fever, it is recommended to choose one of these drugs according to your own situation, and use it according to the instructions or the advice of your doctor.